Straightforward solo build. Keep your shield towards enemies and watch them break against your unstoppable advance. Swap to PP19 if you ever need extra healing, otherwise stick to the House for raw damage. Weapon swapping with a shield equipped can be done by either sprinting or taking cover to put your shield away temporarily.
Immunizer station should be swapped to Ammo station for Resistance mode. You may want to replace Precision with Immunizer on waves where you're expecting to get hit with status effects like cleaner bosses, shotgunner shock grenades, etc. Combat Medic is a powerful talent as well, since it heals your shield as well as you when you use a medkit.
The House, if you don't have one, can just be replaced with a Destructive/Responsive/Predatory MP7 or MP5.
Predatory and Destructive can be interchanged freely with Hurried for more sustained damage, or with Responsive for higher damage output overall.
Shield Damage mods can be replaced with Shield Damage Resilience mods for added survivability if you feel the extra damage is unneeded. For Resistance solo I personally use a 2/2 split of both mods. Balance according to the current activity if you're having trouble surviving/killing enemies.
Purple DTE mods can be replaced with yellow Firearms mods: SP for extra survivability, or CHC for maximum damage output. Note that DTE mods will still outperform CHC mods damage-wise, so try to replace them when possible.